Physical examination shows that Sarita has pain and tenderness consistent with enlarged spleen….

Physical examination shows that Sarita has pain and tenderness consistent with enlarged spleen. She also states that she is experiencing right lateral chest pain; exacerbated on inspiration. Panadeine forte and Ibuprofen were prescribed.
• Explain the types of pain Sarita is experiencing: outlining the pain pathways and the associated neurotransmitters.
• Discuss the positive and negative consequences of her prescribed analgesics on her clinical status. What impact will these medications have on her existing comorbidities, such as infection and bleeding.
Part B (750 words)
As a result of her hospitalisation and symptoms, Sarita is experiencing physical and psychological stress or the “alarm stage” of stress response.
• Analyse the effects of the alarm and resistance stages on Sarita’s immune and cardiovascular systems
• Explain how prolonged stress response could lead to neuro-endocrine exhaustion phase and irreversible systemic dysfunction such overwhelming sepsis.
Part C (1000 words)
Sarita’s diagnosis of leukaemia, the presence of infection as well her clinical findings show that the disease is advanced and potentially life threatening.
• Discuss the immune aspects and cellular changes associated with Sarita’s leukaemia
• Outline Sarita’s risk of bleeding and potential sites of haemorrhage (e.g. mucous membranes) that need to be assessed if her heart rate continues to rise
• Explain how intravascular fluids and pack cells will stabilise Sarita and prevent further deterioration in her condition. What parameters will need continued monitoring
Attachments:
8635894_1_2457-1-1646787081send-word-1–1-.docx