Endochondral Ossification Correctly sequence the steps of endochondral ossification. Osteoblasts beneath the periosteum deposit a thin layer of compact bone. Cartilage tissue breaks down while the periosteum develops. Blood vessels and osteoblasts from the periosteum invade the disintegrating tissue. Masses of hyaline cartilage form models of the future bones. Osteoblasts become osteocytes when the bony matrix completely surrounds them. Osteoblasts form spongy bone in the space once occupied by cartilage.
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